Fecal microbiota transplantation (FMT)
Fecal microbiota transplantation (FMT) is a procedure whereby donor fecal matter is placed into a patient's gastrointestinal system in order to recolonize it with normal gut bacteria that have been killed or suppressed. Primary use is to treat individuals with difficult to treat infections caused by Clostridium difficile (C. difficile). Frozen stool from healthy donors is transplanted to the infected individual's bowel to restore the normal balance of bacteria in the gut.
Status: Decision completed
Why is FMT being reviewed?
Concerns are considered medium for safety, high for efficacy, and low for cost-effectiveness.
Primary criteria ranking
- Safety = Medium
- Efficacy = High
- Cost = Low
Documentation
| Type | Materials |
|---|---|
| Assessment (2016) |
Assessment timeline
- Draft key questions published: May 3, 2016
- Public comment period: May 4 to 17, 2016
- Final key questions published: June 6, 2016
- Draft report published: August 18, 2016
- Public comment period: August 19 to September 19, 2016
- Final report published: October 14, 2016
- HTCC public meeting: November 18, 2016